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Unmasking Pulmonary Parenchymal Changes in Psoriasis Patients: A Radiological Perspective
Müfide Arzu Özkarafakılı1, Mustafa İlteriş Bardakçı1, Onur Sivaz2
1Department of Chest Diseases, Şişli Hamidiye Etfal Training and Research Hospital, 34381 İstanbul, Turkey.
Psoriasis patients often have lung changes, even without symptoms. Current smokers with psoriasis are at higher risk for these pulmonary findings, highlighting the need for screening.
Area of Science:
- Pulmonology
- Dermatology
- Radiology
Background:
- The link between psoriasis and lung conditions is not fully understood.
- Psoriasis patients may develop pulmonary issues without noticeable symptoms.
Purpose of the Study:
- To identify pulmonary parenchymal alterations in asymptomatic psoriasis patients using chest CT scans.
- To explore factors associated with lung involvement in psoriasis.
Main Methods:
- Evaluated 270 psoriasis patients with high-resolution computed tomography (HRCT) scans.
- Analyzed pulmonary function tests, lab data, SF-36 questionnaires, and smoking status.
- Assessed correlations between psoriasis duration, treatments, and lung findings.
Main Results:
- Pulmonary lesions were found in 43% of patients on HRCT scans.
- Reticular changes, nodules, and emphysema were common findings.
- Current smoking, age, and mental health significantly predicted HRCT findings; psoriasis severity (PASI) and treatments did not.
Conclusions:
- Current smokers with psoriasis had nearly double the rate of lung imaging findings compared to non-smokers.
- Pulmonary function tests and CT scans are recommended for psoriasis patients with risk factors like age and smoking history.
- Psoriasis patients can have subclinical lung disease, necessitating proactive screening.
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