Related Experiment Video
Updated: May 25, 2025

Synergetic Use of Neural Precursor Cells and Self-assembling Peptides in Experimental Cervical Spinal Cord Injury
Published on: February 23, 2015
Intranasal Human-Recombinant Nerve Growth Factor Enhances Motor and Cognitive Function Recovery in a Child with
Lorenzo Di Sarno1, Lavinia Capossela1, Serena Ferretti1
1Institute of Pediatrics, Fondazione Policlinico A. Gemelli IRCCS, 00168 Rome, Italy.
Intranasal nerve growth factor (NGF) shows promise for pediatric traumatic brain injury (TBI) recovery. A young boy with severe TBI experienced significant motor and cognitive improvements after receiving human-recombinant NGF (hr-NGF) intranasally.
Area of Science:
- Neuroscience
- Pediatric Neurology
- Regenerative Medicine
Background:
- Pediatric traumatic brain injury (TBI) causes significant mortality and morbidity, with limited regenerative therapies.
- The developing brain is vulnerable, potentially leading to long-term deficits.
- Nerve growth factor (NGF) shows potential for neuroprotection and recovery, with intranasal administration offering a non-invasive route.
More Related Videos
10:45Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling
Published on: May 31, 2017
09:56Promotion of Survival and Differentiation of Neural Stem Cells with Fibrin and Growth Factor Cocktails after Severe Spinal Cord Injury
Published on: July 27, 2014