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Self-Nanoemulsification of Healthy Oils to Enhance the Solubility of Lipophilic Drugs
Published on: July 27, 2022
Lipid Nanoparticles Carrying Essential Oils for Multiple Applications as Antimicrobials
Elenice Francisco da Silva1, Fernanda Aparecida Longato Dos Santos2, Henrique Machado Pires3
1Institute of Biotechnology, Federal University of Uberlandia, Uberlandia 38405-302, Brazil.
Essential oil-based lipid nanoparticles show promise for antimicrobial applications in human health, animal care, and agriculture. These sustainable delivery systems offer alternatives to synthetic antibiotics and pesticides, though market challenges remain.
Area of Science:
- Nanotechnology
- Pharmacology
- Biotechnology
Background:
- Lipid nanoparticles (LNPs) are effective delivery systems for both hydrophobic and hydrophilic molecules.
- Essential oils (EOs) possess inherent antimicrobial properties, making them valuable therapeutic and biopesticidal agents.
- The encapsulation of EOs within LNPs enhances their stability and targeted delivery.
Purpose of the Study:
- To review recent literature (2019-2024) on essential oil-based lipid nanoparticles (EO-LNPs).
- To explore the antimicrobial applications of EO-LNPs in human health, animal care, and biopesticides.
- To identify current challenges and future prospects for EO-LNP technology.
Main Methods:
- Systematic literature review of studies published between 2019 and 2024.
- Analysis of research focusing on EO-LNPs with antimicrobial activities.
- Categorization of applications across human health, animal health, and agriculture.
Main Results:
- EO-LNPs demonstrate significant antiviral, antibacterial, antiprotozoal, and antifungal activities in human healthcare.
- Antibacterial properties of EO-LNPs are highlighted as potential alternatives to synthetic antibiotics.
- Applications in agriculture show efficacy against phytopathogens and pests, supporting sustainable food production.
Conclusions:
- EO-LNPs represent a promising sustainable technology for various health and agricultural applications.
- Further research is needed to fully explore EO-LNP potential in animal health.
- Overcoming market-related challenges is crucial for the widespread adoption of EO-LNP innovations.
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