Chemical Denervation to Relieve Symptoms in Jugular Venous Compression Syndrome: A Case Report

Jugular venous compression syndrome (JVCS) is caused by internal jugular vein compression, leading to headaches, neck discomfort, tinnitus, vertigo, confusion, and blurred vision. These impairments can diminish functional outcomes and compromise quality of life for patients. Literature-based treatments focus on surgical approaches and do not include chemodenervation. However, chemodenervation may be an additional treatment modality to consider. We present the first published case of chemodenervation utilized to successfully treat debilitating neck pain, headaches, and vertigo symptoms for JVCS, resulting in improved functionality and quality of life. This chemical denervation to the anterior neck musculature was trialed in hopes of avoiding surgical intervention. After three treatments, significant symptomatic relief with improved ability to work, improved performance of activities of daily living, and enhanced quality of life were noted. Educating physicians about JVCS and the various treatment modalities available is essential, as less invasive treatment options may not only become available to assist with the functional component of the condition but could also serve as potential alternatives to surgical and endovascular management in carefully selected patients, with the goal of optimizing function and improving quality of life among patients.