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Peritoneal Dialysis in Patients Supported by Left Ventricular Assist Device
Zurab Darbaidze1, Bastian Schmack1, Günes Dogan1
1Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Artificial Organs
|February 26, 2025
Summary
Peritoneal dialysis (PD) is a feasible option for patients with end-stage kidney disease requiring left ventricular assist device (LVAD) therapy. This study shows PD can provide long-term support for LVAD patients with manageable complications.
Area of Science:
- Cardiology
- Nephrology
- Medical Technology
Background:
- Terminal heart failure frequently co-occurs with end-stage kidney disease.
- Peritoneal dialysis (PD) offers patient independence as an alternative to hemodialysis.
- Data on combined PD and left ventricular assist device (LVAD) therapy is limited.
Purpose of the Study:
- To evaluate the feasibility and outcomes of combined PD and LVAD therapy.
- To present the largest cohort study to date on this specific patient population.
Main Methods:
- Retrospective analysis of patients undergoing LVAD implantation between 2000 and 2024.
- Identification of patients on PD therapy prior to or during LVAD support.
- Adverse events classified using the INTERMACS system.
Main Results:
- Nine patients on combined PD and LVAD therapy were identified; mean age was 67 years.
- Cardio-renal syndrome was the primary cause of kidney disease (67%).
- Mean survival after LVAD + PD was 56.5 months, with manageable infection rates (driveline and PD catheter).
Conclusions:
- Peritoneal dialysis is a viable long-term support option for LVAD patients.
- PD offers advantages over hemodialysis, including fewer infections and hemodynamic shifts.
- Combined PD and LVAD therapy can achieve long-term support without major complications.
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