Related Experiment Video
Updated: May 25, 2025

Apparatus for Harvesting Tissue Microcolumns
Published on: October 25, 2018
Advances in regenerative medicine-based approaches for skin regeneration and rejuvenation
Nathalia Silva Dutra Alves1, Gustavo Roncoli Reigado1, Mayara Santos1
1Laboratory of Skin Physiology and Tissue Bioengineering, School of Arts, Sciences and Humanities, University of São Paulo, São Paulo, Brazil.
Abstract:
Significant progress has been made in regenerative medicine for skin repair and rejuvenation. This review examines core technologies including stem cell therapy, bioengineered skin substitutes, platelet-rich plasma (PRP), exosome-based therapies, and gene editing techniques like CRISPR. These methods hold promise for treating a range of conditions, from chronic wounds and burns to age-related skin changes and genetic disorders. Challenges remain in optimizing these therapies for broader accessibility and ensuring long-term safety and efficacy.
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