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[Mathematical model of radiation inactivation of cells]
Abstract:
The analysis was made of the compatibility of several mathematical models for radiation inactivation of mammalian cells with a large number of experimental data and some statistical correlations were revealed between the model survival curve and the approximated experimental dependence. It was shown that the statistical agreement between some model and some set of the experimental data was not a sufficient condition for the theoretical significance of the model. For the most plausible model to be reliably defined by the statistical criteria experimental data should be obtained on many millions of similar biological objects. So one of the theoretical models for radiation inactivation of cells was chosen to give the best description of the known variety of data on mammalian cell inactivation by different types of radiation.