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Peripheral-central correlation study of acupuncture for chronic tinnitus study protocol for a randomized controlled
Da Jiang1, Xiao-Han Huang1, Ke Fang1
1Department of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Frontiers in Medicine
|February 28, 2025
Summary
This study investigates acupuncture's effect on chronic tinnitus by examining auditory function. Results aim to clarify acupuncture's efficacy and mechanisms for tinnitus relief.
Area of Science:
- Neuroscience
- Audiology
- Integrative Medicine
Background:
- Chronic tinnitus significantly impacts quality of life.
- Understanding the auditory system's peripheral and central functions is crucial for tinnitus management.
- Acupuncture is explored as a potential therapeutic intervention.
Purpose of the Study:
- To evaluate peripheral and central auditory function in chronic tinnitus patients.
- To assess the cumulative effects of acupuncture on auditory function in tinnitus.
- To explore the correlation between auditory function and physiological states in healthy individuals.
Main Methods:
- A randomized, assessor-blinded trial involving 72 chronic tinnitus patients.
- Participants allocated 1:1 to acupuncture or sham acupuncture groups.
- Inclusion of 15 healthy controls for physiological state correlation studies.
Main Results:
- Clinical outcomes measured using Tinnitus Handicap Inventory (THI), Auditory Brainstem Response (ABR), and functional Near-Infrared Spectroscopy (fNIRS).
- Data collected at baseline and post-10 treatment sessions.
- Analysis of changes in auditory function and tinnitus severity.
Conclusions:
- Anticipated to enhance understanding of acupuncture's effectiveness for chronic tinnitus.
- Aims to elucidate the underlying mechanisms of acupuncture's action on the auditory system.
- Potential to provide insights into tinnitus pathophysiology and treatment.
