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Updated: May 12, 2026

Preparation and Characterization of SDF-1α-Chitosan-Dextran Sulfate Nanoparticles
Published on: January 22, 2015
The morphologies, physicochemical properties and sustained-release features of short amylose/WPI modified by DBD
Xiaojing Li1, Ting Xu1, Gongjian Fan1
1College of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing, Jiangsu 210037, China; Co-Innovation Center for the Sustainable Forestry in Southern China, Nanjing Forestry University, Nanjing, Jiangsu 210037, China.
Abstract:
To further improve the sustained-release feature of whey protein isolate (WPI) modified by dielectric barrier discharge (DBD) plasma (DWPI) for rutin, short amylose (SA) was used to fabricate DWPI/SA-rutin ternary complex. The physicochemical properties of complexes with different DWPI/SA ratios were investigated and compared. The results showed that the ternary complex nanoparticles gradually tended to be spherical and increased in particle size with the increase of the SA addition. The primary interaction forces between DWPI and SA were hydrogen bond, electrostatic and hydrophobic interactions, which made the ΔH of ternary complex be increased by 649.71 % when the DWPI/SA ratio was 1:1, and the radical scavenging activities of rutin significantly be improved. The cumulative release rate of rutin in the ternary complex was only 27.11 % when the ratio of DWPI/SA was 1:4 after oral and stomach digestion. The research provided a new method for fabricating starch/protein nanocarriers with a sustained-release effect.
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