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Case Report: A Unique Case of Hemophagocytic Lymphohistiocytosis in Heart Transplant

Boaz Elad1, Wojciech Rzechorzek1, Kelly Axsom1

  • 1Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.

Transplantation Proceedings
|February 28, 2025
PubMed

Hemophagocytic lymphohistiocytosis (HLH) is a rare and deadly disease that presents significant diagnostic challenges. The complexity of diagnosis and treatment is further increased among transplant recipients, yet reports on solid organ transplants, and specifically heart transplant recipients, remain scarce. Herein, we elucidate the diagnostic journey, clinical evolution, and therapeutic approach undertaken for a heart transplant recipient afflicted with hemophagocytic lymphohistiocytosis, followed by a review of the literature.

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