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Updated: May 24, 2025

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Editorial: Bridging Generations: The Role of Executive Function in Intergenerational Transmission of Depression
1Nationwide Children's Hospital, Columbus, Ohio; The Ohio State University, Columbus, Ohio.
Abstract:
Maternal depression casts long shadows across generations, influencing cognitive, emotional, and behavioral outcomes in children. Yet, understanding the precise pathways of intergenerational transmission remains a challenge for researchers and clinicians alike. In their recent study, Han et al.1 offer valuable insights into one such pathway: the mediating role of executive function (EF) deficits in the relationship between maternal depressive symptoms and childhood depression. This investigation not only advances the field's understanding of EF but also suggests a role for interventions targeting EF to mitigate the transmission of depressive symptoms.
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