Different Phenotypes of Hidradenitis Suppurativa

Area of Science:

• Dermatology
• Inflammatory Disorders
• Medical Research

Background:

• Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterized by a heterogeneous and fluctuating disease course.
• The diverse natural histories and phenotypes of HS suggest varying responses to therapeutic interventions.

Purpose of the Study:

• To conduct a scoping review of reported hidradenitis suppurativa phenotypes in existing literature.
• To explore potential insights for developing individualized treatment approaches for HS based on phenotype.

Main Methods:

• A comprehensive scoping review methodology was employed.
• Literature search focused on identifying and categorizing reported HS phenotypes.

Main Results:

• The review identified a range of HS phenotypes described in the scientific literature.
• Evidence suggests an association between specific HS phenotypes and treatment responses, though further investigation is warranted.

Conclusions:

• Understanding HS phenotypes is essential for tailoring treatment strategies.
• Additional research on treatment responses and biomarker evaluation is necessary to achieve personalized care for hidradenitis suppurativa.