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Valve-in-Valve Transapical Transcatheter Aortic Valve Replacement with Concomitant Percutaneous Coronary
Abeline R Watkins1, Ryaan El-Andari2, Anoop Mathew3
1Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
The American Journal of Case Reports
|March 2, 2025
Summary
Transapical valve-in-valve transcatheter aortic valve replacement (ViV-TAVR) is a rare but viable option for high-risk patients with severe peripheral vascular disease who are ineligible for traditional transfemoral access. This approach offers a crucial alternative for repeat aortic valve procedures.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Medical Case Reports
Background:
- Valve-in-valve transcatheter aortic valve replacement (ViV-TAVR) is increasingly utilized for elderly, high-risk patients needing repeat aortic valve procedures.
- Common ViV-TAVR access routes include transfemoral, transcarotid, and transsubclavian approaches.
- Severe peripheral vascular disease can contraindicate standard ViV-TAVR approaches, necessitating alternative strategies.
Purpose of the Study:
- To present a rare case of transapical ViV-TAVR in a patient with severe peripheral vascular disease.
- To highlight the utility of the transapical approach for ViV-TAVR when other access routes are contraindicated.
- To demonstrate the feasibility of concomitant percutaneous coronary intervention during transapical ViV-TAVR.
Main Methods:
- A case report detailing the procedure for a 79-year-old male with severe prosthetic valve degeneration and high surgical risk.
- The patient had contraindications for transfemoral, carotid, and subclavian access due to severe peripheral arterial disease.
- The procedure involved transapical ViV-TAVR using a Sapien S3 valve and a left main coronary artery snorkel stent.
Main Results:
- Successful transapical ViV-TAVR was performed in a patient with prohibitive peripheral vascular disease.
- A left main coronary artery snorkel stent was successfully deployed for protection during the procedure.
- This case demonstrates the feasibility of transapical ViV-TAVR in complex, high-risk patients.
Conclusions:
- Transapical ViV-TAVR is a critical alternative for patients ineligible for transfemoral ViV-TAVR due to severe peripheral vascular disease.
- The availability of diverse TAVR approaches is essential for managing high-risk patient populations.
- This case underscores the importance of tailored surgical strategies in complex aortic valve interventions.

