Related Experiment Video
Updated: Jul 14, 2026

Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
Published on: May 27, 2022
Open Globe Injuries in the United States: Analysis of National Trauma Data
Joseph Nygaard1, Collin Hoggard1, Aliya Centner1
1Department of Medical Education, University of Central Florida College of Medicine, Orlando, Florida, USA.
Purpose:
Open Globe Injuries are one of the leading causes of preventable, trauma-related blindness. There is some literature studying the effects of demographic factors as they relate to hospital outcomes. This study characterises trends of Open Globe Injury (OGI) and hospital outcomes based on demographic information utilising the National Trauma Data Bank (NTDB).
Methods:
Using Python programming software, the NTDB was queried for International Classification of Diseases 9th Revision diagnosis codes related to OGI based on the Birmingham Eye Trauma Terminology system. Descriptive statistics were calculated utilising chi-square tests, multivariable adjusted logistic regressions, and ANOVA to process adjusted odds ratio (OR) and means of comparison groups.
Results:
The final analysis included 21,481 patients. Mean age of OGI was lower for Black (40.01 [40.53-41.49]), American Indian (39.08 [37.15-41.00]), and Hispanic (38.24 [37.70-38.77]) populations. OR for Black patients was lower for work-related OGI (0.36 [0.30-0.44]), but higher for drug-positive OGI (1.51 [1.35-1.69]). Black and American Indian patients had increased odds for assault-related injuries and decreased odds for accident-related injuries. Race and ethnicity had little to no effect on mortality, or discharge to home with service, ICU, or step-down unit. Mean age of fall on the same level injuries was (71.28 [70.49-72.07]); all other mechanisms of injury had a mean age < 42.
Conclusions:
Our research offers a unique perspective on OGI utilising the NTDB. The trends identify at-risk populations not previously reported and suggests potential racial effects of public safety, work safety and precautions for open globe injuries.
More Related Videos
07:27Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
04:02Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy
Published on: November 29, 2024
Related Concept Videos
Burn Injuries
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Traumatic Memory
Traumatic Brain Injury l: Introduction