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Sequence Analysis to Phenotype Health Care Patterns in Adults With Musculoskeletal Conditions Using Primary Care
Smitha Mathew1, George Peat1,2, Emma Parry1
1Keele University, Keele, Staffordshire, United Kingdom.
Arthritis Care & Research
|March 3, 2025
Summary
Sequence analysis revealed five distinct healthcare patterns in adult musculoskeletal patients. High healthcare users reported worse outcomes, indicating a need for personalized care strategies.
Area of Science:
- Primary Care Research
- Health Services Research
- Musculoskeletal Health
Background:
- Musculoskeletal (MSK) conditions are a leading cause of disability.
- Understanding patient healthcare journeys in primary care is crucial for effective management.
- Electronic health records (EHRs) offer valuable data for analyzing healthcare patterns.
Purpose of the Study:
- To apply sequence analysis (SA) to phenotype primary care utilization patterns in adult MSK patients.
- To investigate the association between identified healthcare patterns and self-reported patient outcomes.
Main Methods:
- Utilized data from the Multilevel Integrated Data for musculoskeletal health intelligence and Actions program.
- Applied SA to categorize 1,875 adult MSK patients based on primary care consultations, prescriptions, imaging, physiotherapy, and referrals over five years.
- Analyzed associations between sociodemographic factors, self-reported outcomes, and identified healthcare clusters.
Main Results:
- Identified five distinct healthcare pattern clusters: 'increasing consultation and analgesia', 'low consultation and health care use', 'high consultation and health care use', 'low consultation but high analgesia', and 'low consultation but moderate health care use'.
- The 'high consultation and health care use' cluster comprised older, predominantly female patients with obesity, more comorbidities, and from deprived areas.
- Patients in the 'high consultation and health care use' cluster reported significantly worse self-reported outcomes compared to the 'low consultation and health care use' group.
Conclusions:
- Sequence analysis successfully identified five distinct healthcare utilization patterns among primary care patients with MSK conditions.
- Significant variations exist in sociodemographic profiles and self-reported outcomes across these identified healthcare pattern clusters.
- These findings highlight the heterogeneity of MSK patient journeys and their impact on outcomes, suggesting potential for tailored interventions.
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