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Updated: May 8, 2025

Atmospheric-pressure Molecular Imaging of Biological Tissues and Biofilms by LAESI Mass Spectrometry
Published on: September 3, 2010
Life Detection Beyond Earth: Laser-Based Mass Spectrometry for Organics Detection on Solar System Objects
Andreas Riedo1, Nikita J Boeren2, Peter Keresztes Schmidt3
1Physics Institute, University of Bern, Bern, CH-3012 Bern, Switzerland. andreas.riedo@unibe.ch.
Abstract:
The detection and identification of the building blocks of life, from amino acids to more complex molecules such as certain lipids, is a crucial but highly challenging task for current and future space exploration missions in our Solar System. To date, Gas Chromatography Mass Spectrometry has been the main technology applied. Although it has shown excellent performance in laboratory research, it has not yet been able to provide a conclusive answer regarding the presence or absence of a signature of life, extinct or extant, in space exploration. In this contribution we present the current measurement capabilities of our space prototype laser-based mass spectrometer for organics detection. The developed mass spectrometer currently allows the detection and identification of small organic molecules, such as amino acids and nucleobases, at sample concentrations at the level of femtomole mm-2, using the same measurement protocol. The latter is highly relevant to space exploration, since with the instrumentation in use so far only one class of organics can be measured with one instrument configuration.
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