Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Cancer01:30

Skin Cancer

3.0K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
3.0K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

2.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
2.8K
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

1.6K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
1.6K
Burn Injuries01:22

Burn Injuries

2.4K
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
2.4K
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

2.7K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

See One, B1, Treat One: Identifying and Managing Thiamine Deficiency in a Patient With Altered Mental Status.

Cureus·2026
Same author

Dual Antibody Positive Rheumatoid Feet.

Journal of Brown hospital medicine·2026
Same author

Co-occurrence of five chemotherapy induced nail findings.

Journal of hospital medicine·2025
Same author

Herpes zoster ophthalmicus with dependent contralateral edema.

Journal of hospital medicine·2025
Same author

Coffee Bean Sign.

Journal of Brown hospital medicine·2025
Same author

Elephantiasis Nostras Verrucosa.

Journal of Brown hospital medicine·2025
Same journal

Phrenic Nerve Stimulation-Induced Persistent Singultus: A Case of Atrial Lead Dislodgement After Dual-Chamber Pacemaker Implant.

Journal of Brown hospital medicine·2026
Same journal

Purple Urine Bag Syndrome in the Setting of a Percutaneous Nephrostomy: Case Report and Review of the Literature.

Journal of Brown hospital medicine·2026
Same journal

Unprovoked Venous Thromboembolism in a Patient with a Small PNH Clone: A Therapeutic Dilemma.

Journal of Brown hospital medicine·2026
Same journal

From Qi Flow to Air Leak: Bilateral Apical Pneumothoraces After Acupuncture.

Journal of Brown hospital medicine·2026
Same journal

Updates in Hospital Medicine: Nephrology.

Journal of Brown hospital medicine·2026
Same journal

Pseudohypobicarbonatemia: Discordant Bicarbonate Values in Serum and Arterial Samples.

Journal of Brown hospital medicine·2026
See all related articles

Related Experiment Video

Updated: May 24, 2025

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
06:09

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

8.6K

Incidental Cutaneous Melanoma.

Michael Freddy1, Michael E Lazarus1,2, Tyler B Larsen1,2

  • 1Department of Medicine University of California, Los Angeles.

Journal of Brown Hospital Medicine
|March 3, 2025
PubMed
Summary
This summary is machine-generated.

A young man with sepsis and cellulitis was diagnosed with invasive cutaneous melanoma. Early melanoma detection is crucial for prompt treatment and improved patient outcomes.

Keywords:
dermatologymelanomaskin examination

More Related Videos

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
12:37

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

18.1K
A 3D Organotypic Melanoma Spheroid Skin Model
08:49

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

15.6K

Related Experiment Videos

Last Updated: May 24, 2025

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells
06:09

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

8.6K
Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
12:37

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model

Published on: September 7, 2013

18.1K
A 3D Organotypic Melanoma Spheroid Skin Model
08:49

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

15.6K

Area of Science:

  • Dermatology
  • Oncology
  • Infectious Diseases

Background:

  • Sepsis and cellulitis are serious infections requiring immediate medical attention.
  • Invasive cutaneous melanoma is a potentially deadly form of skin cancer.

Observation:

  • A young male patient presented with symptoms of sepsis and cellulitis.
  • During hospitalization, an incidental diagnosis of invasive cutaneous melanoma was made.

Findings:

  • The patient's severe infection masked or occurred concurrently with skin cancer.
  • Melanoma was discovered unexpectedly during the management of infectious conditions.

Implications:

  • Highlights the importance of thorough dermatological evaluation even in patients with acute infections.
  • Emphasizes the need for vigilance in diagnosing melanoma to prevent delayed treatment.
  • Suggests that co-occurring infections may complicate or delay cancer diagnosis.