Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

51
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
51
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

2.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
2.8K
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

31
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
31
Veins of Lower Limbs01:15

Veins of Lower Limbs

407
The human body consists of an intricate network of veins responsible for the crucial task of blood drainage from the lower limbs. These veins can be categorized into two main types: deep veins and superficial veins.
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the...
407
Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

121
Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
121

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dual Antibody Positive Rheumatoid Feet.

Journal of Brown hospital medicine·2026
Same author

Co-occurrence of five chemotherapy induced nail findings.

Journal of hospital medicine·2025
Same author

Herpes zoster ophthalmicus with dependent contralateral edema.

Journal of hospital medicine·2025
Same author

Coffee Bean Sign.

Journal of Brown hospital medicine·2025
Same author

Tophaceous gout.

Journal of hospital medicine·2025
Same author

Incidental Cutaneous Melanoma.

Journal of Brown hospital medicine·2025
Same journal

Phrenic Nerve Stimulation-Induced Persistent Singultus: A Case of Atrial Lead Dislodgement After Dual-Chamber Pacemaker Implant.

Journal of Brown hospital medicine·2026
Same journal

Purple Urine Bag Syndrome in the Setting of a Percutaneous Nephrostomy: Case Report and Review of the Literature.

Journal of Brown hospital medicine·2026
Same journal

Unprovoked Venous Thromboembolism in a Patient with a Small PNH Clone: A Therapeutic Dilemma.

Journal of Brown hospital medicine·2026
Same journal

From Qi Flow to Air Leak: Bilateral Apical Pneumothoraces After Acupuncture.

Journal of Brown hospital medicine·2026
Same journal

Updates in Hospital Medicine: Nephrology.

Journal of Brown hospital medicine·2026
Same journal

Pseudohypobicarbonatemia: Discordant Bicarbonate Values in Serum and Arterial Samples.

Journal of Brown hospital medicine·2026
See all related articles

Related Experiment Video

Updated: May 15, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

989

Elephantiasis Nostras Verrucosa.

Michael E Lazarus1,2, Tyler B Larsen1,3, Jason D Napolitano4,5

  • 1Department of Medicine VA Greater Los Angeles Healthcare System.

Journal of Brown Hospital Medicine
|April 7, 2025
PubMed
Summary
This summary is machine-generated.

Elephantiasis nostras verrucosa is a rare chronic condition causing leg swelling and skin changes due to lymphatic inflammation. This case highlights its presentation in a nursing home resident without typical causes.

Keywords:
Papillomatosiselephantiasislichenificationverrucosawart likewoody induration

More Related Videos

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
08:05

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

Published on: December 9, 2022

3.9K
A Patient-Derived Xenograft Model for Venous Malformation
06:51

A Patient-Derived Xenograft Model for Venous Malformation

Published on: June 15, 2020

5.2K

Related Experiment Videos

Last Updated: May 15, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
06:15

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

989
Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
08:05

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

Published on: December 9, 2022

3.9K
A Patient-Derived Xenograft Model for Venous Malformation
06:51

A Patient-Derived Xenograft Model for Venous Malformation

Published on: June 15, 2020

5.2K

Area of Science:

  • Dermatology
  • Vascular Medicine

Background:

  • The patient presented with chronic, bilateral lower extremity woody induration and papillomatosis, clinically diagnosed as elephantiasis nostras verrucosa.
  • This rare condition results from chronic lymphatic inflammation and fibrosis, distinct from filarial elephantiasis.

Observation:

  • The 76-year-old male resident had a history of deep venous thromboses, chronic venous stasis ulceration, and recurrent cellulitis.
  • He had no history of filarial infection, diabetes, congestive heart failure, or malignancy, and normal thyroid function.

Findings:

  • Clinical diagnosis of elephantiasis nostras verrucosa was established based on the characteristic leg morphology.
  • The patient's presentation mimicked advanced lymphedema with significant skin changes.

Implications:

  • This case underscores the importance of considering non-filarial causes of lymphedema-like conditions.
  • Effective management involves addressing underlying lymphatic dysfunction and associated skin changes.