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Updated: Jan 9, 2026
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Mycosis Fungoides
Leslie Ojeaburu1, Tyler Larsen1,2
1Medicine University of California, Los Angeles.
Journal of Brown Hospital Medicine
|March 3, 2025
Summary
Mycosis fungoides, a type of cutaneous T-cell lymphoma, presents diagnostic challenges due to varied skin symptoms. This case highlights managing widespread disease with phototherapy and topical treatments.
Area of Science:
- Dermatology
- Hematology
- Oncology
Background:
- Mycosis fungoides is a rare cutaneous T-cell lymphoma (CTCL).
- Early diagnosis is difficult due to variable skin presentations and atypical biopsy findings.
- CTCL primarily affects the skin.
Observation:
- An elderly patient presented with generalized, chronic pruritus.
- The patient exhibited widespread cutaneous T-cell lymphoma.
- The presentation mimicked other dermatologic conditions, complicating initial diagnosis.
Findings:
- The case highlights the diagnostic challenges of mycosis fungoides.
- Despite extensive skin involvement, the patient's condition is being managed.
- Treatment involves a combination of phototherapy and topical antipruritic medications.
Implications:
- This case underscores the importance of considering CTCL in patients with persistent, unexplained skin conditions.
- Effective management strategies can be employed even in advanced stages of mycosis fungoides.
- Further research into early diagnostic markers for CTCL is warranted.
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