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Updated: May 24, 2025

Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps
Published on: February 9, 2017
Impact of temporal order selection on clustering intensive longitudinal data based on vector autoregressive models
Yaqi Li1, Hairong Song2, Bertus Jeronimus3
1Department of Pediatrics, Health Sciences Center, University of Oklahoma.
The lowest order (LO) approach generally outperformed the highest order (HO) for identifying clusters in longitudinal data. Combining the LO approach with Gaussian mixture models (GMM) yielded the best results for cluster identification.
Area of Science:
- Longitudinal Data Analysis
- Statistical Modeling
- Psychometrics
Background:
- Model-based clustering of multivariate intensive longitudinal data relies on consistent temporal order across individuals.
- Psychological and behavioral processes often exhibit between-individual differences in temporal order.
- Existing methods for setting temporal order include using the highest order (HO) or lowest order (LO) for all processes, with limited study on their impact.
Purpose of the Study:
- To examine the performance of HO and LO methods in vector autoregressive (VAR)-based clustering.
- To compare Gaussian mixture models (GMM) and k-means algorithms within a two-step VAR-based clustering procedure.
- To identify optimal approaches for clustering individuals based on their longitudinal data dynamics.
Main Methods:
- A simulation study was conducted to evaluate the performance of HO and LO methods.
- The study utilized Gaussian mixture models (GMM) and k-means clustering algorithms.
- A two-step vector autoregressive (VAR)-based clustering procedure was implemented across various data conditions.
Main Results:
- The lowest order (LO) approach demonstrated superior performance in cluster identification compared to the highest order (HO) approach.
- The highest order (HO) approach was more favorable for estimating cluster-specific dynamics.
- Gaussian mixture models (GMM) generally outperformed k-means clustering.
- The combination of the LO approach and GMM yielded the best outcomes for cluster identification.
Conclusions:
- The choice of temporal order (LO vs. HO) significantly impacts VAR-based clustering results.
- Gaussian mixture models (GMM) combined with the LO approach are recommended for robust cluster identification in longitudinal data.
- Findings offer practical recommendations for empirical applications of model-based clustering techniques.
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