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    Area of Science:

    • Neuroimaging
    • Artificial Intelligence
    • Computational Neuroscience

    Background:

    • Limited high-quality datasets hinder deep learning in neuroimaging.
    • On-the-fly synthetic data generation is computationally intensive.
    • Pre-generated data is inflexible and incurs high storage costs.

    Purpose of the Study:

    • Introduce Wirehead, a scalable in-memory pipeline for efficient on-the-fly synthetic data generation.
    • Improve performance and reduce computational demands for deep learning in neuroimaging.
    • Address data availability and storage challenges in the field.

    Main Methods:

    • Developed a scalable in-memory data pipeline (Wirehead).
    • Decoupled data generation from training using parallel processes.
    • Utilized MongoDB for efficient handling of large datasets.
    • Evaluated Wirehead with SynthSeg for synthetic brain segmentation data generation.

    Main Results:

    • Achieved near-linear performance gains with parallel generators.
    • Demonstrated a 15.7x throughput increase with 16 generators.
    • Reduced model training time from 7 days to 9 hours with 20 generators.
    • Successfully handled terabytes of data, minimizing storage costs.

    Conclusions:

    • Wirehead significantly accelerates deep learning experimentation cycles in neuroimaging.
    • The pipeline offers a flexible, modular, and fault-tolerant solution.
    • Enables more ambitious neuroimaging research through distributed deep learning.