[Coagulation disorder after severe traumatic brain injury: case report and literature review]

Objective: To improve the understanding of the diagnosis and treatment of coagulation disorders after severe head trauma. Methods: One case of coagulation disorder after severe traumatic brain injury was reported and the literature was reviewed. Results: A 70-year-old female was admitted to the hospital with 10 hours of unconsciousness after head injury. The patient underwent emergency epidural hematoma removal, decompression, and epidural hematoma drainage, and then coagulation disorder occurred, followed by myocardial infarction with heart failure and venous thrombosis of the lower limbs. After multiple infusions of prothrombin complex, application of low molecular weight heparin and active anti-infective therapy, the patient eventually regained coagulation function. Conclusion: For trauma patients, especially those with head injuries, it is crucial to test coagulation as early as possible, take measures to maintain coagulation function, apply plasma or fibrinogen in the early stages, and be vigilant for later hypercoagulable states and thrombosis, with timely anticoagulation as needed.