Indigenous Peoples Living with Multiple Sclerosis in Canada

Area of Science:

• Neurology
• Public Health
• Indigenous Health

Background:

• Indigenous Peoples in Canada (First Nations, Inuit, Métis) are the youngest and fastest-growing demographic.
• Multiple sclerosis (MS) is a leading cause of nontraumatic neurological disability in young adults.
• Canada has one of the world's highest MS prevalences, yet data on Indigenous populations is scarce.

Purpose of the Study:

• To review existing literature on multiple sclerosis (MS) in Indigenous Peoples in Canada.
• To identify knowledge gaps and explore global data on MS in Indigenous populations.
• To propose strategies for improving MS research and care for Indigenous Peoples.

Main Methods:

• Narrative review of published studies on MS in Indigenous Peoples in Canada.
• Exploration of international studies concerning MS in Indigenous populations.
• Analysis of barriers and facilitators for culturally safe research with Indigenous communities.

Main Results:

• Limited Canadian data suggests a lower prevalence of MS among Indigenous Peoples, but with potentially increased disease severity.
• Global studies on Indigenous populations with MS are also sparse.
• Key challenges include a lack of trust, historical injustices, and inadequate cultural safety in research.

Conclusions:

• There is a critical need for more culturally appropriate and community-driven research on MS among Indigenous Peoples in Canada.
• Implementing cultural safety training and respecting data sovereignty are essential for effective engagement.
• Collaborative efforts between healthcare professionals and Indigenous communities are vital to improve understanding and care for MS.