Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ablepharon macrostomia syndrome.

A Hornblass, D M Reifler

    American Journal of Ophthalmology
    |May 15, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Ablepharon macrostomia syndrome, a severe congenital disorder, involves eyelid and lip abnormalities. Surgical reconstruction of eyelids and mouth in one patient showed developmental progress and improved corneal opacity.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Enlarged pupillary membranes.

    Journal of pediatric ophthalmology and strabismus·2014
    Same author

    Friedrich August von Ammon (1799-1861).

    Documenta ophthalmologica. Advances in ophthalmology·2000
    Same author

    Tarsal switch procedure for the surgical rehabilitation of the eyelid and socket deficiencies of the anophthalmic socket.

    Ophthalmic plastic and reconstructive surgery·1999
    Same author

    Sclerosing sweat duct carcinoma of the eyelid margin: unusual presentation of a rare tumor.

    Ophthalmology·1999
    Same author

    Pseudomonal eyelid necrosis: clinical characteristics and review of the literature.

    Ophthalmic plastic and reconstructive surgery·1998
    Same author

    Infantile myofibromatosis of orbital bone. A case report with computed tomography, magnetic resonance imaging, and histologic findings.

    Ophthalmology·1997
    Same journal

    Reply to Comment on Visual Field Progression in Glaucoma Patients with Delayed Follow-Up.

    American journal of ophthalmology·2026
    Same journal

    Comment on: "Safety and efficiency reducing retinopathy of prematurity guideline sensitivity: an external validation using a large US-based dataset".

    American journal of ophthalmology·2026
    Same journal

    Reply to Comment on "Clinicopathological and Imaging Distinction Between Ocular Adnexal MALT Lymphoma and IgG4-Related Ophthalmic Disease".

    American journal of ophthalmology·2026
    Same journal

    Comment on: Visual Field Progression in Glaucoma Patients With Delayed Follow-Up.

    American journal of ophthalmology·2026
    Same journal

    Corneal sensitivity changes and nerve plexus abnormalities in noninfectious anterior uveitis.

    American journal of ophthalmology·2026
    Same journal

    Role of Menopausal Hormone Therapy on Strabismus, Strabismus Surgery, and Reoperation Rates.

    American journal of ophthalmology·2026
    See all related articles

    Area of Science:

    • Medical Genetics
    • Congenital Disorders
    • Surgical Reconstruction

    Background:

    • Ablepharon macrostomia syndrome is a rare, severe congenital condition.
    • It presents with multiple anomalies including eyelid absence, macrostomia, and ambiguous genitalia.

    Observation:

    • A case report details a patient with ablepharon macrostomia syndrome.
    • The patient exhibited typical features of the syndrome, including eyelid and lip malformations.
    • Ocular findings included nystagmus, corneal opacities, and retinal abnormalities.

    Findings:

    • A three-stage surgical procedure successfully reconstructed the eyelids using retroauricular full-thickness grafts.
    • Subsequent mouth reconstruction was also successful.
    • The patient demonstrated developmental improvements, including sitting unassisted and grasping objects.

    Related Experiment Videos

  • Initial corneal opacities improved, allowing visualization of the pupil in one eye.

    • Implications:

    • This case highlights the potential for surgical intervention in severe congenital conditions like ablepharon macrostomia syndrome.
    • Reconstructive surgery can lead to functional and aesthetic improvements.
    • Early surgical management may positively impact developmental outcomes in affected children.