Related Experiment Video
Updated: Jun 17, 2026

11:58
Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
Published on: August 11, 2015
15.4K
Technical Tips for CT-Guided Fibrin Glue Patching of CSF-Venous Fistulas
1From the Department of Radiology, The Permanente Medical Group, Kaiser Permanente Medical Center, Santa Clara, California mark.d.mamlouk@kp.org.
AJNR. American Journal of Neuroradiology
|March 4, 2025
Summary
Fibrin glue patching effectively treats cerebrospinal fluid (CSF)-venous fistulas by targeting the venous drainage pattern. This minimally invasive technique aims to sever the connection between cysts and veins for successful treatment.
Area of Science:
- Neurosurgery
- Interventional Radiology
Background:
- Cerebrospinal fluid (CSF)-venous fistulas are abnormal connections between the CSF space and the venous system.
- Traditional treatments include transvenous embolization and surgical ligation.
- Routine epidural patching differs in targeting strategy.
Purpose of the Study:
- To illustrate technical tips for effective fibrin glue patching in treating CSF-venous fistulas.
- To highlight a targeted approach to the venous drainage pattern.
Main Methods:
- Fibrin glue patching specifically targets the venous drainage pattern of CSF-venous fistulas.
- Key target locations include the cyst-vein junction, paravertebral wall, and direct cyst puncture.
- The goal is to occlude the abnormal connection between the cyst and the vein.
Main Results:
- Fibrin glue patching is presented as an effective treatment modality.
- Technical nuances for successful application at specific target sites are demonstrated.
- The procedure aims to disconnect the cyst from the venous system.
Conclusions:
- Fibrin glue patching offers an effective therapeutic option for CSF-venous fistulas.
- Targeted application to the venous drainage pattern is crucial for success.
- This technique provides a minimally invasive approach to address these complex fistulas.

