Related Experiment Video

Updated: May 24, 2025

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches
09:47

Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches

Published on: December 15, 2023

938

Dysarthria Detection with Deep Representation Learning for Patients with Parkinson's Disease

Chen Zhang, Chen Gong, Yanan Sui

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |March 5, 2025
    PubMed

    Abstract:

    Dysarthria is a very common motor speech symptom in Parkinson's disease impairing normal communications of patients. Detection of dysarthria could assist clinical diagnosis and intervention of Parkinson's disease, provide monitoring approach for treatment-related side effects, and lead to effective speech therapy to prevent further communication and social deficits. Applying machine learning techniques to speech analysis for patients offers more resource-efficient, accessible and objective tools for screening and assessment of dysarthria. In this study, we constructed a multi-task speech dataset recorded from 600 participants with high data diversity to facilitate the development of detection models. We established a remote data acquisition and end-to-end prediction pipeline with deep representation learning, compared the performance with different feature-based learning and classification methods, and achieved a superior accuracy of over 90%. Different affecting factors were analyzed for model performance. Our proposed framework demonstrates the potential of developing and deploying an automated self-monitoring approach of dysarthria for patients with Parkinson's disease, which could benefit a large-scale population and their disease managements.

    More Related Videos

    Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
    11:12

    Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

    Published on: July 16, 2014

    22.2K
    Targeted Training of Ultrasonic Vocalizations in Aged and Parkinsonian Rats
    11:00

    Targeted Training of Ultrasonic Vocalizations in Aged and Parkinsonian Rats

    Published on: August 8, 2011

    19.7K

    Related Experiment Videos

    Last Updated: May 24, 2025

    Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches
    09:47

    Author Spotlight: Advancing Alzheimer's Research – Exploring Early Detection and Multi-Omics Approaches

    Published on: December 15, 2023

    938
    Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
    11:12

    Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

    Published on: July 16, 2014

    22.2K
    Targeted Training of Ultrasonic Vocalizations in Aged and Parkinsonian Rats
    11:00

    Targeted Training of Ultrasonic Vocalizations in Aged and Parkinsonian Rats

    Published on: August 8, 2011

    19.7K

    Related Concept Videos

    Parkinson's Disease: Treatment01:24

    Parkinson's Disease: Treatment

    182
    Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
    Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
    182
    Parkinson's Disease: Overview01:15

    Parkinson's Disease: Overview

    419
    Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
    419
    Neural Regulation01:37

    Neural Regulation

    39.1K
    Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
    39.1K

    Articles linked to this work by shared authors, journal, and citation graph.

    Targeting the extracellular vesicle-immune axis in prostate cancer: mechanisms of immune evasion and emerging therapeutic strategies.

    Biochemical pharmacology·2026

    Immediate urinary continence after continence-preserving holmium laser enucleation versus transurethral plasmakinetic prostatectomy for benign prostatic hyperplasia: a single-center comparative cohort study.

    World journal of urology·2026

    Integrative Bioinformatics and Experimental Validation Reveal that METTL9 Drives Lung Adenocarcinoma Progression via TGF-β/Smad-Mediated EMT Activation.

    Frontiers in bioscience (Landmark edition)·2026

    Chemical and sensory profiling of fermented, washed, and artificially flavored coffee beans: Insights into flavour quality, authenticity, and food safety implications.

    Food chemistry·2026

    Design, synthesis, biological evaluation, DFT and molecular docking studies of novel isoxazolines containing cyclic amide.

    Bioorganic chemistry·2026

    Air-permeable hydrogels through viscoelastic phase separation of aerogels.

    Nature·2026

    Analysis of End-Tidal CO2 Variability During Plateau Waves Episodes: An Information Theoretic Approach.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    AI and Tomosynthesis for Breast Cancer Molecular Subtyping: A step toward precision medicine.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    Towards Sustainable Protein Recovery from Biological Waste: Assessing Polyethersulfone-based Microfiltration.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    Analysis of the cardiovascular response to standardized polymicrobial peritonitis experimental model.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    Automated Wrist Ultrasound Image Bone Enhancement and Segmentation Using Deep Learning.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    A Deep Learning approach for Depressive Symptoms assessment in Parkinson's disease patients using facial videos.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

    Cerebrolysin as an adjunct to speech-language therapy in post-stroke Wernicke's aphasia: a case report.

    Journal of medicine and life·2026

    Comparing Traditional Motor Speech Practice to Contextualized Speech Practice in Preschoolers With Childhood Apraxia of Speech.

    American journal of speech-language pathology·2026

    Predictors of Retention in Positive Airway Pressure Therapy: Motivation, Psychological Status, and Sleep Symptom Severity.

    Clinical and experimental otorhinolaryngology·2026

    Understanding Adherence to Mandibular Advancement Device Therapy for Obstructive Sleep Apnea in Chronic Spinal Cord Injury: A Mixed-Methods Study.

    Topics in spinal cord injury rehabilitation·2026

    Spinal cord stimulation for concurrent improvement of consciousness and spasticity following severe traumatic brain injury: a case study.

    Frontiers in neuroscience·2026

    A Preliminary Investigation into the Impact of Re-Testing and Voice Hygienic Advice on Dysphonia Severity Index Scores.

    Journal of voice : official journal of the Voice Foundation·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us