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Updated: May 5, 2026
Isolation of Neonatal Extrahepatic Cholangiocytes
Published on: June 5, 2014
Cholestasis and congenital neuroblastoma in a preterm neonate: a case report
Surasak Puvabanditsin1, Melissa Guillermo2, Yisha Cheng2
1Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, 1 Robert Wood Johnson Place, New Brunswick, NJ 08903, USA.
Objectives:
Neuroblastoma (NB) is one of the most common tumor during perinatal period. The clinical features of NB occurring in fetuses and neonates differ from that in the older age groups. Frequently, Congenital neuroblastomas are incidentally detected prenatally. Clinical presentations of NBs in neonates are highy variable.
Case Presentation:
A 24-day old preterm 32 weeks' gestation male neonate developed cholestasis that lead to the diagnosis of stage MS neuroblastoma. There was no NB primary site identified.
Conclusions:
To the best of our knowledge, this is the first case report of metastatic NB (Stage MS) in a preterm neonate presenting with cholestsis but without any identifiable adrenal or extra-adrenal primary.
