INDIVIDUAL ARTICLE: NECOM 5: Algorithm for the Treatment and Supportive Management of Targeted Therapy-Related...

Area of Science:

• Oncodermatology
• Cancer Therapeutics
• Clinical Dermatology

Background:

• Substantial cancer burden in Nordic countries necessitates improved patient care.
• Targeted therapies enhance survival but can cause cutaneous adverse events (cAEs).
• Lack of practical clinical tools for managing cAEs in cancer patients and survivors.

Framework:

• The Nordic European Cutaneous Oncodermatology Management (NECOM) project aims to address cAEs.
• NECOM 5 focuses on developing a practical algorithm for targeted therapy-related cAEs (TTcAEs).
• Previous NECOM studies covered general cAEs, radiation therapy, and immunotherapy-related cAEs.

Implementation:

• A consensus-based practical algorithm for TTcAEs was developed by the NECOM panel.
• The algorithm incorporates systematic review findings, expert opinion, and Nordic clinical settings.
• It includes general skin care and prevention, plus specific management for common TTcAEs like rash and hand-foot syndrome.

Implications:

• TTcAEs significantly impact cancer patient and survivor quality of life.
• The NECOM algorithm provides a valuable clinical tool for managing TTcAEs.
• Implementation of this algorithm can improve cancer patient outcomes and quality of life.