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Assessing the impact of uncertainty in a VMAT plan for H&N cancer considering patient setup error (PSE)

Arvind Kumar1, Kiran Sharma2, C P Bhatt3

  • 1Graphic Era Deemed to Be University, Dehradun, Uttarakhand, 248002, India; All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, 249203, India.

Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine
|March 5, 2025
PubMed

Keywords:
HNCPatient setup error (PSE)Plan robustnessUncertaintyVMAT

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The atomic mass of an element varies due to the relative ratio of its isotopes. A sample's relative proportion of oxygen isotopes influences its average atomic mass. For instance, if we were to measure the atomic mass of oxygen from a sample, the mass would be a weighted average of the isotopic masses of oxygen in that sample. Since a single sample is not likely to perfectly reflect the true atomic mass of oxygen for all the molecules of oxygen on Earth, the mass we obtain from this particular...
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The confidence interval is the range of values around the mean that contains the true mean. It is expressed as a probability percentage. The interpretation of a 95% confidence interval, for instance, is that the statistician is 95% confident that the true mean falls within the interval. The upper and lower limits of this range are known as confidence limits. The confidence limits for the true mean are estimated from the sample's mean, the standard deviation, and the statistical factor 't,' or...
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