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"Shunt-ing" down obesity with novel endogenous metabolites
Victor J Pai1, Alan Saghatelian1
1Clayton Foundation Peptide Biology Laboratories, The Salk Institute for Biological Studies, La Jolla, CA, USA.
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Obesity is a growing public health issue that has recently been transformed through the advent of new medicines. However, our understanding of the pathways and mechanisms that regulate energy balance in mammals is still developing. Recent discoveries on this front include an exciting new finding that there exists a novel class of metabolites in humans and mice that can regulate obesity in rodents.
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