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Incidental Detection of Meningioma on 18 F-Flutemetamol PET
Young-Sil An1, So Young Moon2, Tae Hoon Roh3
1Department of Nuclear Medicine and Molecular Imaging.
Abstract:
Meningioma is typically a benign tumor that may incidentally be found on imaging. This case demonstrates the utility of 18 F-flutemetamol (FMM) PET/CT in an 80-year-old woman evaluated for memory decline. Although the scan was performed for dementia assessment, it revealed an incidental mass in the frontal region. Early-phase PET showed relatively low uptake, while delayed-phase imaging displayed intense uptake of 18 F-FMM. Magnetic resonance imaging and surgical pathology confirmed the lesion as a meningioma. This report may aid in interpreting incidental mass lesions on 18 F-FMM PET, providing a reference for physicians who may encounter similar findings.
Insights
18F-flutemetamol PET/CT can reveal incidental meningiomas in dementia evaluations. Delayed imaging shows intense uptake, aiding diagnosis of these benign brain tumors.
Area of Science:
- Neurology
- Nuclear Medicine
- Oncology
Background:
- Meningiomas are typically benign tumors often discovered incidentally.
- Dementia evaluations frequently involve advanced imaging techniques.
Purpose of the Study:
- To demonstrate the utility of 18F-flutemetamol (FMM) PET/CT in identifying incidental meningiomas.
- To provide a reference for interpreting incidental lesions on FMM PET/CT scans.
Main Methods:
- Case study of an 80-year-old woman evaluated for memory decline.
- Utilized 18F-flutemetamol (FMM) PET/CT with early and delayed phase imaging.
- Confirmed findings with Magnetic Resonance Imaging (MRI) and surgical pathology.
Main Results:
- An incidental frontal mass was detected during a dementia assessment FMM PET/CT scan.
- The lesion showed low initial uptake but intense uptake in delayed-phase imaging.
- MRI and pathology confirmed the incidental finding as a meningioma.
Conclusions:
- 18F-FMM PET/CT can be valuable for detecting incidental meningiomas.
- Delayed-phase imaging is crucial for identifying characteristic intense uptake in meningiomas.
- This case aids physicians in interpreting incidental masses found during FMM PET/CT scans.

