Mucolytic Therapy in COPD: Patient Usage and Preferences in Real-World Italian Settings

Area of Science:

• Pulmonology
• Patient-reported outcomes
• Pharmacotherapy

Background:

• Chronic obstructive pulmonary disease (COPD) management often involves mucolytic therapies.
• Patient adherence and preferences significantly impact treatment effectiveness.
• The Italian COPD Patient Association surveyed its members to understand mucolytic usage patterns.

Purpose of the Study:

• To investigate the reasons behind widespread mucolytic use in COPD patients.
• To identify patient preferences for mucolytic formulations and usage duration.
• To explore patient awareness of mucolytic properties and factors influencing adherence.

Main Methods:

• An online survey was distributed to 2814 members of the Italian COPD Patient Association.
• The survey comprised nine questions developed in consultation with respiratory specialists.
• Responses were collected via email from 502 participants.

Main Results:

• 78% of participants used mucolytics in the prior six months, with 54.5% prescribed and 23.5% OTC.
• Water-soluble sachets and effervescent tablets were preferred formulations.
• Usage varied, with 43.4% using mucolytics for excessive mucus and 35.5% using them regardless; 26.5% used entire packages.

Conclusions:

• Findings highlight the need for patient-centered approaches in COPD care.
• Healthcare providers should consider individual patient preferences for improved adherence.
• Personalized advice can enhance overall outcomes for patients with chronic obstructive pulmonary disease.