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Related Concept Videos

Cognitive Therapy01:25

Cognitive Therapy

57
Cognitive therapy, pioneered by Aaron T. Beck in the 1960s, is a structured approach to addressing psychological distress by focusing on the influence of thoughts on emotions and behaviors. All cognitive therapies involve the basic assumption that human beings have control over their feelings, and that how individuals feel about something depends on how they think about it. Unlike psychoanalytic methods that delve into unconscious processes or humanistic approaches emphasizing...
57
Rational Emotive Behavior Therapy01:24

Rational Emotive Behavior Therapy

40
Cognitive-behavioral therapies (CBTs) are grounded in the belief that our thoughts profoundly influence our emotions and actions. Advocates of CBT emphasize three core assumptions: first, that cognitions are identifiable and measurable; second, that they are central to psychological functioning; and third, that irrational or maladaptive beliefs can be replaced with rational and adaptive ones. This transformative approach to therapy has paved the way for specific models such as Albert...
40
Interpersonal Psychotherapy01:25

Interpersonal Psychotherapy

19
Interpersonal psychotherapy (IPT) is a structured, time-limited therapeutic approach initially developed to treat depression. It integrates key concepts from psychodynamic, humanistic, and cognitive-behavioral therapies, making it a uniquely eclectic framework. The therapy is rooted in the interpersonal theories of Adolph Meyer and Harry Stack Sullivan, as well as John Bowlby's attachment theory, and focuses on the interplay between interpersonal relationships and emotional well-being.
19
Electroconvulsive Therapy01:30

Electroconvulsive Therapy

22
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
22
Behavior Therapy01:22

Behavior Therapy

38
Behavior therapy incorporates diverse techniques rooted in classical conditioning principles to address maladaptive behaviors and anxiety disorders. These methods aim to reduce avoidance behaviors, foster adaptive coping mechanisms, and alter associations between stimuli and responses, making them effective in a wide range of therapeutic contexts.
Exposure therapy is a cornerstone of behavioral treatment for anxiety disorders. It involves systematic exposure to feared stimuli, either in real...
38
Beck's Cognitive Therapy01:25

Beck's Cognitive Therapy

34
Cognitive therapy is a psychological approach designed to address distortions in thinking, which can lead to negative emotions and unrealistic beliefs. These cognitive distortions often influence how individuals interpret and respond to situations, exacerbating emotional distress. Below are some prevalent cognitive distortions, their characteristics, and examples of how they manifest in thought processes.
Arbitrary Inference
Arbitrary inference involves making conclusions without sufficient...
34

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Related Experiment Video

Updated: May 24, 2025

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Psilocybin-Assisted Cognitive Behavioral Therapy for Adults with Major Depressive Disorder: Rationale and Treatment

Marc J Weintraub1, Jessica K Jeffrey1, Charles S Grob1,2

  • 1Department of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, California, USA.

Psychedelic Medicine (New Rochelle, N.Y.)
|March 6, 2025
PubMed
Summary

This study explores psilocybin-assisted CBT (PA-CBT) for major depressive disorder. It aims to optimize this novel therapy, combining cognitive-behavioral therapy with psilocybin, for improved patient outcomes.

Keywords:
CBTPATdepressionpsychedelicpsychosocialtherapy

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Pharmacology

Background:

  • Psilocybin shows acute antidepressant effects in major depressive disorder.
  • Limited research exists on the accompanying therapy (psychedelic-assisted therapy, PAT).

Purpose of the Study:

  • To present the protocol for empirically testing psychosocial therapy adjoining psilocybin treatment.
  • To optimize this therapeutic approach for adults with major depressive disorder.

Main Methods:

  • A 12-session psilocybin-assisted CBT (PA-CBT) protocol for 30 adults with major depressive disorder.
  • Two psilocybin administration sessions (10 and 25 mg) following specific PA-CBT sessions.
  • Assessment of mood, functioning, schemas, and affective experiences post-administration and post-treatment.

Main Results:

  • Preliminary data on feasibility, safety, and acceptability of PA-CBT.
  • Evaluation of psychosocial effects of PA-CBT.

Conclusions:

  • Results will inform future randomized clinical trials for depression and other mental health conditions.
  • Hypotheses regarding cognitive and affective mediating mechanisms will be explored.