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Multiscale Formulation for Assessment of Electroosmotic Flow in Paper-Based Microfluidics.

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This study introduces multiscale modeling for fluid and electroosmotic flows in paper-like porous materials. The technique accurately predicts flow properties, validating with experimental data for microfluidic applications.

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Area of Science:

  • Multiscale modeling
  • Porous media flow
  • Microfluidics

Background:

  • Paper-based microfluidics utilize porous materials for fluidic devices.
  • Accurate modeling of flow dynamics is crucial for device design and performance.

Purpose of the Study:

  • To develop and apply multiscale techniques for modeling pressure-driven and electroosmotic flows in paper-like porous materials.
  • To validate the multiscale approach against experimental data and direct numerical simulations.

Main Methods:

  • A representative volume element (RVE) approach was used to model microstructures.
  • Stokes flow and Helmholtz-Smoluchowsky electrokinetics were solved at the microscale.
  • Homogenized Darcy flow and effective electroosmotic permeability were calculated at the macroscale.

Main Results:

  • The multiscale technique accurately predicted pressure-driven and electroosmotic flow behavior.
  • Effective permeability and electroosmotic properties were derived for macroscale simulation.
  • Validation was achieved through comparison with experimental data for Whatman 1 and Munktel 00A papers.

Conclusions:

  • The developed multiscale technique is effective for modeling complex flows in paper-based microfluidics.
  • Proposed microcell structures can represent paper properties for predicting fluidic and electrical behavior.
  • This approach enables prediction of other phenomena like capillary imbibition and dispersion.