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Published on: October 26, 2016
Applications of Dynamic Online Sample Preconcentration Techniques in Chiral Capillary Electrophoresis
Fumihiko Kitagawa1, Koji Otsuka2,3
1Department of Frontier Materials Chemistry, Graduate School of Science and Technology, Hirosaki University, Hirosaki, Aomori, Japan.
Abstract:
This review highlights applications of online sample preconcentration techniques in capillary electrophoresis (CE) analyses of enantiomers from 1995 to 2025. Various preconcentration techniques based on the analyte velocity change in two or three discontinuous solution system, including field-amplified sample stacking, sweeping, transient isotachophoresis, pH-mediated stacking, and their modified and combined techniques, have been employed to enrich and separate optical isomers in CE. More than 50 published research articles retrieved from Google Scholar databases from the years 1995 to 2025 described the application of dynamic online sample preconcentration techniques to chiral CE analyses. This review provides comprehensive tables listing the applications of the online sample preconcentration techniques in chiral CE.
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