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CCT: a coordinate conversion tool for hepatitis B virus
Trevor Graham Bell1, Mukhlid Yousif2, Anna Kramvis1
1Hepatitis Virus Diversity Research Unit, Department of Internal Medicine, University of the Witwatersrand, Johannesburg.
Abstract:
The hepatitis B virus (HBV) genome has ∼3 200 nucleotides, coding for seven proteins in four overlapping open reading frames (ORFs). Comparison of genomic coordinates between different samples and/or published literature requires manual conversion. An online tool is presented to convert nucleotide or amino acid positions between ORFs, regions and domains of the HBV genome. The user enters a position into an interactive web page, which then shows this position in all other applicable ORFs, regions or domains and plots it on a diagrammatic representation of the HBV genome. This tool assists researchers to convert coordinates, thereby facilitating comparisons between samples.
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