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Survey Health Data on Allergic Rhinitis (AR) and Asthmatic Symptoms and Blood Samples (IgE Sensitizations) in

Susanne Kutzora1,2, Jonas Mehrl2,3, Jonas Huß1

  • 1Department of Occupational and Environmental Health/Epidemiology, Bavarian Health and Food Safety Authority, Munich, Germany.

Pediatric Pulmonology
|March 7, 2025
PubMed

Insights

This study found that children with IgE sensitizations are more likely to have allergic rhinitis (AR) and asthma symptoms. Parental asthma and low birth weight are key risk factors for developing these conditions in children.

Area of Science:

  • Pediatric Allergy and Immunology
  • Environmental Health
  • Epidemiology

Background:

  • Investigated the link between IgE sensitization and allergic rhinitis (AR) and asthmatic symptoms in children.
  • Assessed prevalence of AR, asthma, and sensitization in a German pediatric cohort.

Purpose of the Study:

  • To determine the association between serum IgE sensitizations and self-reported allergic rhinitis and asthmatic symptoms.
  • Identify risk factors for allergic diseases in early childhood.

Main Methods:

  • Survey of 1190 children (aged 60-64 months) using questionnaires on allergic symptoms and medical history.
  • Serum IgE sensitization analysis in 340 children.
  • Regression analysis to assess associations between sensitization and health outcomes.

Main Results:

  • 118 out of 340 children (34.7%) showed sensitization to at least one allergen.
  • Sensitized children reported higher rates of AR symptoms, wheeze, and asthma.
  • Parental asthma and physician-diagnosed asthma (OR 4.79) were strongly associated with childhood asthma.

Conclusions:

  • Parental asthma and underweight at birth are significant risk factors for allergic symptoms and asthma in children.
  • IgE sensitization is linked to increased reporting of allergic rhinitis and asthma symptoms.
Abstract

Keywords:
allergic rhinitisallergychildrenhealth monitoringsensitization

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