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Updated: May 23, 2025

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
09:14

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

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Intraplaque Hemorrhage Is a Key Finding in Sudden Cardiac Death Resulting From Coronary Vasospasm

Akihiro Takasaki1, Hiromasa Ito1, Tairo Kurita1

  • 1Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Mie, Japan.

JACC. Case Reports
|March 7, 2025
PubMed

Insights

Intraplaque hemorrhage, a key factor in plaque instability, was linked to acute myocardial infarction and sudden cardiac death in a patient experiencing coronary vasospasm. This case highlights critical cardiovascular event associations.

Area of Science:

  • Cardiovascular Medicine
  • Pathology
  • Radiology

Background:

  • Intraplaque hemorrhage is a significant driver of atherosclerotic plaque instability and progression.
  • It is independently associated with adverse cardiovascular outcomes, including sudden cardiac death and coronary vasospasm.

Purpose of the Study:

  • To report a unique case demonstrating the link between coronary vasospasm, intraplaque hemorrhage, and acute myocardial infarction.
  • To emphasize the role of intraplaque hemorrhage in sudden cardiac death associated with coronary vasospasm.

Main Methods:

  • Case report presentation.
  • Comprehensive cardiovascular imaging of the culprit coronary artery.

Main Results:

  • A patient presented with cardiopulmonary arrest due to acute myocardial infarction.
  • Coronary vasospasm was identified as the cause, with intraplaque hemorrhage observed in the affected vessel.

Conclusions:

  • This case underscores the critical association between intraplaque hemorrhage, coronary vasospasm, and potentially fatal cardiac events.
  • Comprehensive imaging is crucial for understanding these complex cardiovascular pathologies.

Keywords:
acute coronary syndromecardiovascular diseaseimaging

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