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Percutaneous device closure for Paravalvular leak- A single centre experience.
Uday B Khanolkar1, Meemansa Kashyap Buch1, Satish C Govind1
1Narayana Institute Of Cardiac Sciences, Bengaluru, India.
Indian Heart Journal
|March 8, 2025
Summary
Percutaneous device closure effectively treats paravalvular leaks (PVLs) after surgery. This transcatheter approach offers a safe and successful option for patients experiencing significant PVLs, improving outcomes.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Paravalvular leak (PVL) is a complication after surgical valve replacement, occurring in 5-17% of cases.
- Significant PVLs can lead to heart failure, hemolysis, and other adverse events.
- Current management options for PVLs can be limited or invasive.
Purpose of the Study:
- To evaluate the safety and efficacy of percutaneous device closure for significant paravalvular leaks.
- To assess the technical and procedural success rates of transcatheter PVL closure.
- To determine the feasibility of this minimally invasive approach for PVL management.
Main Methods:
- A retrospective analysis of patients undergoing transcatheter device closure for PVLs.
- Closure procedures were performed for leaks in mitral, aortic, and combined positions.
- Data collected included technical success, procedural success, and patient outcomes.
Main Results:
- Transcatheter device closure was performed in 45 PVLs across 42 patients.
- Successful closure was achieved in the mitral position (23 cases), aortic position (20 cases), and combined positions (2 cases).
- High rates of technical success (93.33%) and procedural success (91.11%) were observed.
Conclusions:
- Percutaneous device closure is a safe and effective treatment for symptomatic paravalvular leaks.
- Transcatheter PVL closure provides a viable alternative to surgical re-intervention.
- This minimally invasive technique demonstrates favorable success rates in managing significant PVLs.

