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Spectrum of benign intracranial hypertension in children and adolescents
Insights
Benign intracranial hypertension (BIH) in children and adolescents often presents without papilledema. Early diagnosis and treatment, including shunting, are crucial for symptom relief and accurate management.
Area of Science:
- Pediatric Neurology
- Neuro-ophthalmology
Background:
- Benign intracranial hypertension (BIH) is a condition affecting children and adolescents.
- Accurate diagnosis can be challenging, with potential pitfalls even with CT scanning.
Purpose of the Study:
- To review recent cases of BIH in pediatric patients.
- To describe the clinical manifestations and diagnostic challenges of BIH in children and adolescents.
Main Methods:
- Retrospective review of 23 pediatric cases of BIH.
- Analysis of clinical presentations, diagnostic methods, and treatment outcomes.
Main Results:
- BIH occurred in similar proportions of males (11) and females (12).
- Papilledema was absent in 12 patients, highlighting a diagnostic challenge.
- Transient visual obscurations were common in patients without papilledema.
- Lumboperitoneal shunting provided immediate symptom relief in 6 patients with persistent symptoms.
Conclusions:
- Papilledema is not a prerequisite for diagnosing BIH in children and adolescents.
- A variety of etiologies exist for BIH in this age group.
- Accurate diagnosis requires careful consideration of clinical signs beyond papilledema.
Abstract:
A review of the most recent 23 cases of benign intracranial hypertension (BIH), admitted to the War Memorial Children's Hospital in London, Ontario, provided a compendium of the clinical manifestations of this disorder in children and adolescents. Although CT scanning lets one feel more secure in making such a diagnosis, pitfalls still exist. The sex ratio was 11 males to 12 females. Age groupings were: 0-6 years (2 patients); 7-12 years (10); 13-17 years (11). No postviral etiologies were encountered in patients more than 13 years of age. In only 6 cases could no definite etiology be established. Of great importance was the recognition of the condition in 12 patients who did not have papilledema. Elevated intracranial pressure was proven in 8 of these by lumbar CSF pressure monitoring, in 1 by lumbar punctures and in 1 infant with split cranial sutures. Absence of papilledema was confirmed by ophthalmological examination. Transient visual obscurations were very common in this group. In 6 patients, persistent signs and symptoms in spite of vigorous drug therapy prompted lumboperitoneal shunting, with immediate relief of symptoms in all. In only 1 case has the diagnosis of BIH proven to be in error. A warning leak from an aneurysm caused papilledema and headache, and a normal CT scan supported the diagnosis until the patient had a major hemorrhage weeks later. BIH has a variety of causes in children and adolescents, and papilledema is not a prerequisite for diagnosis.
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