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Fever Among Pertussis Cases Reported Through Enhanced Pertussis Surveillance, 2015-2022.

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Fever is not a common symptom of pertussis (whooping cough). However, this study found that 10% of pertussis cases reported fever, indicating it can occur and shouldn't rule out the diagnosis.

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case definitionfeverpertussissurveillancevaccine-preventable disease

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Area of Science:

  • Infectious Diseases
  • Pediatric Medicine
  • Public Health

Background:

  • Pertussis, also known as whooping cough, is a highly contagious respiratory infection.
  • Fever is often not recognized as a typical symptom of pertussis.
  • Accurate diagnosis is crucial for effective treatment and public health control.

Purpose of the Study:

  • To investigate the occurrence and characteristics of fever in confirmed pertussis cases.
  • To assess the impact of fever on the clinical presentation of pertussis.
  • To inform diagnostic considerations for pertussis, especially in patients with cough illness.

Main Methods:

  • Analysis of a large cohort of 7840 pertussis cases.
  • Data collected through the Centers for Disease Control and Prevention's Enhanced Pertussis Surveillance.
  • Inclusion criteria focused on cases with cough onset between 2015 and 2022.

Main Results:

  • Fever was reported in 10% of the analyzed pertussis cases.
  • The presence of fever did not exclude pertussis as a potential diagnosis.
  • This finding challenges the traditional view of pertussis presentation.

Conclusions:

  • Fever can be a presenting symptom in pertussis.
  • Clinicians should consider pertussis in patients with cough illness, even if fever is present.
  • Public health surveillance data highlights the variability in pertussis symptoms.