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    Area of Science:

    • Public Health
    • Epidemiology
    • Vaccinology

    Background:

    • Measles is a highly contagious respiratory virus that can cause significant outbreaks, severe complications, hospitalizations, and fatalities.
    • Two doses of the measles vaccine are 97% effective and recommended for individuals aged 12 months and older to maintain population immunity and prevent outbreaks.
    • A large measles outbreak originating in west Texas in January 2025 spread to New Mexico, resulting in 99 reported cases, with about half affecting adults.

    Purpose of the Study:

    • To describe the New Mexico Department of Health's (NMDOH) multimodal communication and vaccination outreach strategy implemented during a statewide measles outbreak.
    • To assess the impact of the NMDOH's strategy on measles-mumps-rubella (MMR) vaccine administration in a large, rural state.

    Main Methods:

    • NMDOH implemented a comprehensive strategy including a centralized webpage, a telephone helpline, and mobile vaccination clinics to disseminate information and resources.
    • The strategy aimed to overcome challenges in communication and vaccine access across a geographically vast and rural state.
    • Data on MMR vaccine doses administered were compared between January 1-September 26, 2025, and the same period in 2024.

    Main Results:

    • The NMDOH's outreach strategy coincided with a 55% increase in MMR vaccine doses administered statewide during the specified period in 2025 compared to 2024.
    • The implemented communication and access strategies were associated with increased vaccine uptake during the outbreak.

    Conclusions:

    • Coordinated public communication and enhanced access to the MMR vaccine are crucial for effective measles outbreak response, particularly in large, rural regions.
    • Multimodal strategies can successfully support vaccine administration and contribute to controlling infectious disease outbreaks.