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Anti-Phospholipase A2 Receptor Antibody Testing to the Rescue
A S Nath1, Siddharth Herur1, Gangadhar Taduri1
1Department of Nephrology, Nizams Institute of Medical Sciences, Hyderabad, Telangana, India.
Serological testing for anti-phospholipase A2 receptor antibodies (antiPLA2R Ab) aids in diagnosing membranous nephropathy. This case highlights antiPLA2R Ab utility in patients with autosomal dominant polycystic kidney disease.
Area of Science:
- Nephrology
- Immunology
Background:
- Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults.
- Diagnosis traditionally relies on kidney biopsy, which can be challenging in certain patients.
- Anti-phospholipase A2 receptor antibodies (antiPLA2R Ab) are established biomarkers for primary MN.
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