Related Experiment Video
Updated: May 23, 2025
07:36
Analysis of Raw and Processed Cyperi Rhizoma Samples Using Liquid Chromatography-Tandem Mass Spectrometry in Rats with Primary Dysmenorrhea
Published on: December 23, 2022
1.4K
The GC MS Study of One Ayurvedic Formulation, Navayasa Churnam
Aparna Sudhan1, K Prabhu2, Sumathi Jones3
1Research Scholar, Department of Anatomy, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Journal of Pharmacy & Bioallied Sciences
|March 10, 2025
Summary
This study identified key bioactive compounds in Navayasa Churnam using GC-MS analysis. The findings support its traditional uses for various ailments, highlighting the value of combining ancient wisdom with modern science.
Area of Science:
- Ayurvedic medicine
- Phytochemistry
- Pharmacognosy
Background:
- Navayasa Churnam is a traditional Ayurvedic formulation.
- It is historically used to manage anemia, cardiac conditions, dermatological issues, hemorrhoids, and jaundice.
Purpose of the Study:
- To conduct a Gas Chromatography-Mass Spectrometry (GC-MS) analysis of Navayasa Churnam.
- To identify the bioactive chemical constituents present in the formulation.
Main Methods:
- Navayasa Churnam was procured from a certified Ayurvedic supplier in Chennai, India.
- Standard preparation protocols were followed.
- Gas Chromatography-Mass Spectrometry (GC-MS) was employed for compound identification.
Main Results:
- GC-MS analysis identified several bioactive compounds, including Asarone (sedative, antioxidant), 17-Octadecynoic acid methyl ester (anti-inflammatory), n-Pentadecanol (antimicrobial), and Piperine (bioavailability enhancer, anti-inflammatory).
- Other identified compounds include n-Butyl cinnamate (anti-inflammatory, antioxidant), Chloroacetic acid esters (antiviral, antimicrobial), 2-ynyl o-anisate (analgesic), Carnosic acid, and Ethyl iso-allocholate.
Conclusions:
- The identified phytochemical profile validates the traditional therapeutic applications of Navayasa Churnam.
- This research emphasizes the synergy between traditional Ayurvedic knowledge and modern analytical methods for herbal medicine validation.
