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Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
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Latex Fruit Syndrome and Periodontitis - A Missing Link
Nivedha Menon1, D Hema1, Saranya Aathilingaperumal1
1Department of Periodontics, Sree Balaji Dental College and Hospital, Chennai, Tamil Nadu, India.
Journal of Pharmacy & Bioallied Sciences
|March 10, 2025
Summary
Natural rubber latex (NRL) allergy is linked to food hypersensitivity, known as latex-fruit syndrome. Research suggests chitinase enzymes connect NRL allergy, latex-fruit syndrome, and periodontitis, but more studies are needed.
Area of Science:
- Immunology
- Oral Medicine
- Biochemistry
Background:
- Latex allergy affects 6% of the population, with higher prevalence in healthcare workers.
- Natural rubber latex (NRL) allergy is associated with hypersensitivity to plant-derived foods (latex-fruit syndrome) in 30-50% of cases.
- Chitinase enzymes have been implicated in both periodontitis and latex-fruit syndrome.
Purpose of the Study:
- To explore the relationship between chitinase, periodontitis, and latex-fruit syndrome.
- To identify gaps in current research regarding latex-fruit syndrome and periodontitis.
Main Methods:
- A systematic review of 15 articles was conducted.
- The review analyzed existing literature on chitinase, periodontitis, and latex-fruit syndrome.
Main Results:
- A clear relationship was found between chitinase and periodontitis.
- A clear relationship was also established between chitinase and latex-fruit syndrome.
- The direct link between latex-fruit syndrome and periodontitis remains under-investigated.
Conclusions:
- Chitinase plays a role in both periodontitis and latex-fruit syndrome.
- Further evidence-based research is necessary to understand the connection between latex-fruit syndrome and periodontitis.
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