Related Experiment Video
Updated: May 23, 2025

09:41
Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
11.4K
"Will the Real Demyelinating Disorder Please Stand Up?": From the National Multiple Sclerosis Society Case Conference
Aisha Elfasi1, Myla D Goldman2, Claire Riley3
1Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD.
Neurology(R) Neuroimmunology & Neuroinflammation
|March 10, 2025
Abstract:
A 46-year-old man presented with progressive painful monocular vision loss and left leg paresthesias. Workup demonstrated multifocal demyelinating lesions and CSF-restricted oligoclonal bands. He was diagnosed with multiple sclerosis (MS), but follow-up testing was notable for positive myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG). We discuss implications and clinical considerations for MOG-IgG positivity in MS.

