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Updated: May 23, 2025
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Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
Published on: May 12, 2023
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Laryngeal Neuroendocrine Carcinoma
Dibangkar Das1, Vikas Sharma1, Niharika Mishra2
1Department of Otolaryngology, Command Hospital (EC), Kolkata, India.
Summary
This case report details an extremely rare subglottic small cell neuroendocrine carcinoma. Early diagnosis and aggressive treatment, including chemoradiotherapy, led to a favorable response in this laryngeal cancer patient.
Area of Science:
- Oncology
- Otorhinolaryngology
- Pathology
Background:
- Neuroendocrine tumors of the larynx are rare, accounting for 1% of laryngeal tumors.
- Subglottic neuroendocrine carcinoma is exceptionally rare, with few reported cases.
- These tumors can present atypically, mimicking other conditions.
Purpose of the Study:
- To report a rare case of subglottic small cell neuroendocrine carcinoma.
- To highlight the diagnostic challenges and management of this rare laryngeal malignancy.
- To emphasize the importance of early diagnosis and aggressive treatment.
Main Methods:
- A 56-year-old male presented with hoarseness and dyspnea.
- Diagnostic evaluation included Micro laryngoscopy and Biopsy under General Anesthesia (GA).
- Histopathological examination (HPE) confirmed small cell neuroendocrine carcinoma.
Main Results:
- The patient was diagnosed with subglottic small cell neuroendocrine carcinoma.
- No secondary primary tumor or distant metastases were identified.
- The patient showed a favorable response to chemoradiotherapy.
Conclusions:
- Small cell neuroendocrine carcinoma of the subglottic larynx is aggressive and rare.
- Prompt diagnosis and aggressive management are crucial for patient outcomes.
- Close monitoring is necessary due to high recurrence and metastasis risk.
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