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Mobile Electronic Patient-Reported Outcomes and Interactive Support During Breast and Prostate Cancer Treatment:
Marie-Therése Crafoord1, Joakim Ekstrand2, Kay Sundberg1
1Division of Nursing, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
JMIR Cancer
|March 11, 2025
Summary
Digital health tools using electronic patient-reported outcomes (ePROs) and interactive support show potential cost-effectiveness in cancer care. While improving quality-adjusted life years (QALYs), variability in healthcare costs necessitates further research for definitive conclusions.
Area of Science:
- Oncology
- Health Economics
- Digital Health Interventions
Background:
- Digital interventions with ePROs can improve cancer treatment supportive care.
- Early symptom detection and timely management are key benefits.
- Economic evaluations are crucial for these digital health tools.
Purpose of the Study:
- To conduct a cost-utility analysis of an app for ePRO and interactive support.
- To evaluate the impact on patient healthcare utilization and costs from a payer's perspective.
- To explore the cost-effectiveness of digital supportive care in cancer treatment.
Main Methods:
- Two randomized controlled trials (RCTs) for breast and prostate cancer patients.
- Mapping EORTC QLQ-C30 to EQ-5D-3L for quality-adjusted life years (QALYs) calculation.
- Calculating incremental cost-effectiveness ratios (ICERs) using various cost inclusion scenarios.
Main Results:
- Intervention groups showed fewer QALYs lost compared to controls (P<.001).
- Breast cancer RCT: ICERa €202,368, ICERb €49,903, ICERc €13,213.
- Prostate cancer RCT: ICERa -€1,092,136, ICERb €745,987, ICERc €13,118.
Conclusions:
- ePRO and interactive support apps offer a small QALY improvement at low cost.
- Cost-effectiveness is dependent on considered costs; variability introduces uncertainty.
- Larger societal perspective studies are needed; insights into acute care utilization are provided.
