Related Experiment Video
Updated: May 23, 2025
14:38
Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis
Published on: January 4, 2019
18.0K
Comparative Evaluation of Bilateral Earlobe Cleft Repair with and Without Platelet Rich Plasma Injection- In vivo
Priti Talele1, Lakshmi Shetty1, Shreya Jeetendra Raut1
1Department of Oral and Maxillofacial Surgery, Dr. D.Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, 411018 India.
Summary
Platelet-rich plasma (PRP) injections enhance earlobe cleft repair, reducing pain and scarring. This study demonstrates PRP
Area of Science:
- Plastic Surgery
- Regenerative Medicine
Background:
- Earlobe clefts present a significant aesthetic concern.
- Platelet-rich plasma (PRP) is known for its wound healing properties but has not been extensively studied for earlobe cleft repair.
Purpose of the Study:
- To compare the efficacy of wound healing in bilateral earlobe cleft repair with and without intradermal platelet-rich plasma (PRP) injection.
Main Methods:
- A study involving 50 patients with bilateral earlobe clefts undergoing repair using the cross-stitch technique.
- Intradermal PRP was injected on one side, while the other side served as a control.
- Post-operative evaluation of pain and scar formation at 24 hours, 8 days, and 15 days.
Main Results:
- Patients receiving PRP injections reported lower pain scores at 8 days post-operatively compared to the control group.
- Scar evaluation using the Stony Brook Scar Evaluation Scale (SBSES) showed improved outcomes in the PRP group at 15 days.
- The technique using PRP demonstrated statistically significant improvements in healing and scar reduction (p < 0.01, 0.05).
Conclusions:
- Intradermal PRP injection combined with the cross-stitch technique is a simple, cost-effective method for earlobe cleft repair.
- PRP promotes healing, reduces scar formation, and helps maintain earlobe length, contour, and integrity.
- This study provides evidence for the effectiveness of PRP in a large sample size for earlobe cleft repair.
