A comparative study of adsorbed tetanus vaccine

A study is reported in which 197 volunteers were given adsorbed tetanus vaccine from two different sources. Using an ELISA system all pre-vaccination sera were screened. Both pre- and post-vaccination sera from volunteers with an initial antibody level of less than 1 iu/ml were then titrated and the antibody response analyzed. The results confirm that both vaccines produced an excellent antibody response with little difference in reactogenicity.